刘丽宏

教授，主任药师，专硕导师

研究领域：新药研究；代谢性疾病的机制研究；精准用药研究；药代动力学及I期临床研究

电  话：（010）84205559

电子邮箱：hongllh@126.com

教育背景

第四军医大学理学博士（2001）

西安医科大学理学硕士（1997）

沈阳药科大学理学学士（1990）

工作经历

2021.03至今     中日友好医院药学部 中日友好医院科技中心（科研处）主任、总药师、药学部主任、药物临床试验机构主任

2012.03-2021.03  首都医科大学附属北京朝阳医院药事部 主任、总药师

2003.11-2012.03  第二炮兵总医院药学部 主任

社会兼职

中国药学会药学服务专委会主任委员；

中国女医师协会药学专业委员会主任委员；

中华医学会临床药学专委会常委；

中国科学技术协会第六批首席科学传播专家；

北京药学会临床研究与转化专业委员会主任委员；

北京医学会临床药学专业委员会副主任委员；

《中国临床药理学杂志》副主编

代表性论文（近一年）

1.Ying Wang, Zhikang Ye, Long Ge, Reed A Siemieniuk, Xin Wang, Yingkai Wang, Liangying Hou, Zhuo Ma, Thomas Agoritsas, Per Olav Vandvik,

Anders Perner, Morten H M？ller, Gordon H Guyatt, Lihong Liu*. Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients:

systematic review and network meta-analysis. BMJ. 2020, 368:l6744. (Q1, IF=30.223)

2.Zhikang Ye, Annika Reintam Blaser, Lyubov Lytvyn, Ying Wang, Gordon H. Guyatt, J. Stephen Mikita, Jamie Roberts, Thomas Agoritsas,

Sonja Bertschy, Filippo Boroli, Julie Camsooksai, Bin Du, Anja Fog Heen, Jianyou Lu, José M. Mella, Per Olav Vandvik, Robert Wise,

Yue Zheng, Lihong Liu*, Reed A.C. Siemieniuk. Gastrointestinal bleeding prophylaxis for critically ill patients: a clinical practice guideline.

BMJ. 2020, 368:l6722. (Q1, IF=30.223)

3.Wang X, Wang S, Yu X, Ma Z, Wang H, Yang J, Liu L. Impact of pharmacist-led medication therapy management in ambulatory elderly patients

with chronic diseases. Br J Clin Pharmacol. 2021 Jul;87(7):2937-2944. (Q1, IF=4.335)

4.Sun X, Wang X, Zhang J, Zhao Z, Feng X, Liu L, Ma Z. Efficacy and safety of PARP inhibitors in patients with BRCA-mutated advanced breast cancer:

A meta-analysis and systematic review. Breast. 2021 Dec;60:26-34. doi: 10.1016/j.breast.2021.08.009. Epub 2021 Aug 21.

PMID: 34455227; PMCID: PMC8399371. (Q1, IF=4.38)

5.Lu W, Guo Q, Ma Z, Liu L, Zhao Z. Lenvatinib and osteonecrosis of the jaw: A pharmacovigilance study. Eur J Cancer. 2021 Jun;150:211-213.

doi: 10.1016/j.ejca.2021.03.046. Epub 2021 May 3. (Q1, IF=7.275)

6.Ma Z, Sun X, Zhao Z, Lu W, Guo Q, Wang S, You J, Zhang Y, Liu L. Risk of pneumonitis in cancer patients treated with PARP inhibitors:

A meta-analysis of randomized controlled trials and a pharmacovigilance study of the FAERS database. Gynecol Oncol. 2021 Aug;162(2):496-505. (Q1, IF=4.623)

7.Du P, Wang GY, Zhao R, An ZL, Liu LH. Eicosanoid Metabolomic Profile of Remdesivir Treatment in Rat Plasma by High-Performance Liquid Chromatography

Mass Spectrometry. Front Pharmacol. 2021 Sep 29;12:747450. doi: 10.3389/fphar.2021.747450. PMID: 34658883; PMCID: PMC8511316. (Q1, IF=5.81)

8.Zhao R, An Z, Sun Y, Xia L, Qiu L, Yao A, Liu Y, Liu L. Metabolic profiling in early pregnancy and associated factors of folate supplementation:

A cross-sectional study. Clin Nutr. 2021 Sep;40(9):5053-5061. doi: 10.1016/j.clnu.2021.01.012. Epub 2021 Jan 23. PMID: 34455263. (Q1, IF=7.324)

9.Yang S, Hu T, Liu H, Lv YL, Zhang W, Li H, Xuan L, Gong LL, Liu LH. Akebia saponin D ameliorates metabolic syndrome (MetS) via remodeling gut

microbiota and attenuating intestinal barrier injury. Biomed Pharmacother. 2021 Jun;138:111441. (Q1, IF=6.529)

10.Sun X, Ma Z, Guo Q, Zhao Z, Liu L. Ibrutinib-related skin cancer: A pharmacovigilance study from the Food and Drug Administration Adverse Event

Reporting System. Eur J Cancer. 2022 Jan;160:277-278. doi: 10.1016/j.ejca.2021.10.034. Epub 2021 Dec 2. PMID: 34865944. (Q1, IF=9.162)

11.Yang H, Sun Y, Yu X, Hu X, Wang W, Zhang X, Liu L. Clinical Impact of the Adaptation of Initial Tacrolimus Dosing to the CYP3A5 Genotype After

Kidney Transplantation: Systematic Review and Meta-Analysis of Randomized Controlled Trials. Clin Pharmacokinet. 2021 Jul;60(7):877-885. (Q1, IF=6.447)

12.Li P, Peng J, Li Y, Gong L, Lv Y, Liu H, Zhang T, Yang S, Liu H, Li J, Liu L. Pharmacokinetics, Bioavailability, Excretion and Metabolism Studies

of Akebia Saponin D in Rats: Causes of the Ultra-Low Oral Bioavailability and Metabolic Pathway. Front Pharmacol. 2021 Apr 15;12:621003. (Q2, IF=4.225)

荣誉奖励