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方翼 专硕导师

 

方翼

主任药师,博士生导师

研究领域:临床试验、临床药理、定量药理

电话:(01066583834

电子邮箱:fygk7000@163.com

 

教育背景

中国海洋大学医学博士(2003-2007)

华西医科大学理学学士(1990-1995)

 

 

工作经历

2013.08-至今    北京大学医学部药学院硕士生导师

2018.08-至今    广州医科大学药学院   兼职博士生导师

2008.12-至今    北京大学人民医院I期临床试验研究室主任,副主任药师、主任药师、教授

1995.07-2008.12   中国人民解放军总医院药材处临床药理研究室,实习研究员、主管药师、副主任药师

 

 

社会兼职

2020-至今   中国药理学会临床药理学专业委员会,副主任委员

2019-至今   中国药理学会定量药理专业委员会,副主任委员

2018-至今   中国药理学会药物临床试验专业委员会,常务委员

 

 

代表性论文(近一年)

1.Wenliang Dong, Min Chen, Suping Niu, Bianzhen Wang, Lin Xia, Jiaxue Wang, Tiantian Shen, Qian Wang, Jie Lv, Gang Liu, Huayiing Fan, Zhenwei Xie,

Fan Xie, Youzhong An, Qingshan Zhen, Huiying Rao, Haifeng Song, Yi Fang. Pharmacokinetic bioequivalence, safety,and immunogenicity of GB222,

a bevacizumab biosimilar candidate, and bevacizumab in Chinese healthy males: a randomized clinical  trial.. Expert Opinion on Biological Therapy.

10.1080/14712598.2021.1954517.(通讯作者,IF=4.388, JCR Q2区)

2.Lin Xia,Tiantian Shen,Wenliang Dong,Feng Su,Jiaxue Wang,Qian Wang,Suping Niu,Yi Fang. Comparative efficacy and safety of 8 GLP-1RAs

in patients with type 2 diabetes: a network meta-analysis. Diabetes Research and Clinical Practice.

2021;177:108904(1-12) ( 通讯作者,IF =5.602,JCR Q1区)

3.Suping Niu, Yan Li, Wenliang Dong, Lin Xia, Tiantian Shen, Jiaxue Wang, Qian Wang, Tan Zhang, Minjie Zhang, Gang Liu, Danjie Guo, Yi Fang.

A randomized study on the bioequivalence of desloratadine in Chinese healthy subjects and the association of different metabolic phenotypes

with UGT2B10 and CYP2C8 genotypes. Current Drug Metabolism. 2020,21:1031-1039. ( 通讯作者,IF = 2.960,JCR Q2区)

4.Wenliang Dong, Xiaoyan Nie, Jiaxue Wang, Lin Xia, Lin Cai, Qian Wang, Wei Wang, Weixing Fu, Qi Wang, Tiantian Shen, Huaying Fan, Suping Niu,

Yimin Cui, Qingshan Zheng, Jianzhong Zhang, Yi Fang. Study protocol for a randomized, double-blind, multicenter, phaseI/II dose escalation and

expansion trial of GR1501 in patients with plaque psoriasis. BMJ OPEN. 2020;10:e039067.doi:10.1136/bmjopen-2020-039067.

(通讯作者,IF=2.692, JCR Q2区)

5.Wenliang Dong, Min Chen, Jiaxue Wang, Lin Xia, Qian Wang, Xiaoyan Nie, Yufei Feng, Yi Fang. rHuPH20-facilitated subcutaneous administration

of monoclonal antibodies in cancer therapy. Immunotherpy. 10.2217/imt-2020-0204.(通讯作者,IF=4.196, JCR Q3区)

6.Tiantian Shen, lin Xia, Wenliang Dong, Jiaxue Wang, Feng Su, Suping Niu, Qian Wang, Yi Fang. A Systematic Review and Meta-analysis:

Safety and Efficacy of Mesenchymal stem Cells Therapy for Heart Failure. Current Stem Cell Research &Therapy. 2021;16:354-365.

(通讯作者,IF=3.828, JCR Q3区)

7.Chang Liu , Wenliang Dong , Lin Xia , Jie Lv , Daoli Jiang , Qian Wang , Mei Wang , Maofeng Wu , Jingwei Miao , Tao Tao , Dong Wang , Lili Zheng ,

Shiguang Su , Lizhong Liu , Yi Fang. The Safety and Tolerability of a Humanized Rabbit Monoclonal Antibody (SSS07) in Healthy Adults: Randomized

Double-Blind Placebo-controlled Single Ascending Dose Trial. International Immunopharmacology. 2021; 91:107263(1-9) ( 通讯作者,IF =4.939,JCR Q1区)

8.Huaning Kang, Jinhua Zhang, Xiaoting Zhang, Guicheng Qin, Ke Wang, Zhenyu Deng, Yi Fang, Guihong Chen. Effects of sacubitril/valsartan in patients

with heart failure and chronic kidney disease: A meta-analysis. European Journal of Pharmacology. 884(2020)173444:1-7.

(通讯作者,IF=3.263, JCR Q2区)

9.Jiaxue Wang, Suping Niu, Wenliang Dong, Li Wei, Lun Ou, Tan Zhang, Liangbi Zhang, Xiaoyan Nie, Qian Wang, Tiantian Shen, Qi Wang, Lin Xia,

Gang Liu, Jiting Jing, Qing shan Zheng, Haifeng Song & Yi Fang. A randomized phase I clinical trial comparing the pharmacokinetic, safety,

and immunogenicity of potential biosimilar recombinant human HER2 monoclonal antibody for injection and trastuzumab in healthy Chinese adults.

Expert Opinion On Investigational Drugs. 2020,29(7):755-762. (通讯作者,IF=5.081, JCR Q1区)

10.Huihui Dai, Chang Liu, Peijuan Li, Zhangfeng Mai, Xiaoming Tan, Sijing Chen, Ziling Zhou, Zhiben Tang, Jingwei Miao, Lizhong Liu, Yi Fang.

Risk of Dyslipidaemia Associated with VEGF/VEGFR Inhibitors A Meta-analysis. Translational Oncology. 2020; 13:100779(1-8)

( 通讯作者,IF = 3.558,JCR Q2区)。

11.Chen Li, Tenghua Wang, Yongmei Li, Tan Zhang, Qi Wang, Jin He, Li Wang, Lujin Li, Ning Yang, Yi Fang. Probiotics for the treatment of women

with bacterial vaginosis: a systematic review and meta-analysis of randomized clinical trials.European Journal of Pharmacology.

2019;864:172660(1-9)  (通讯作者,IF=3.17, JCR Q2区)。

12.Jiaxue Wang, Tiantian shen, Qi Wang, Tan Zhang, Lujin Li, Yu Wang & Yi Fang. The long-term efficacy of cytokine-induced killer cellular therapy

for hepatocellular carcinoma: a meta-analysis. Immunotherapy. 2019;11(15):1325-1335. ( 通讯作者,IF = 3.028,JCR Q3区)。

13.Tan Zhang, Minjie Zhang, Li’an Zu, Chang Liu, Qian Wang, Qi Wang, Wei Wang, Yitong Wang, Yannan Zang, Zhenwei Xie, Shi Chen, Mei Wang,

Qingshan Zheng, Zhanguo Li, Guihong Chen,Yi Fang. Safety and Tolerability of a Single Dose T0001 in Chinese Healthy Adult Volunteers:

A First-in-Human Ascending Dose Study. Brazilian journal of pharmaceutical science. 2020;58:e18447(1~8)(通讯作者,IF = 0.814,JCR Q4区)

 

荣誉奖励

2020年度北京大学人民医院优秀党员

2019年度北京大学人民医院先进工作者