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黄琳 学硕导师

 

 

黄琳

主任药师、副教授、硕士生导师

研究领域:药物基因组学、治疗药物监测与药物个体化应用研究

电话:(01088325750

电子邮箱:huanglin@pkuph.edu.cn

 

教育背景

华中科技大学同济医学院医学博士(2008)

华中科技大学同济医学院医学学士(2004)

 

 

工作经历

2022.08至今                北京大学人民医院药学部,党支部书记

2020.08至今                北京大学人民医院药剂科,副教授

2017.10-2018.09         美国匹兹堡大学药学院,访问学者

2017.08至今                北京大学人民医院药剂科,主任药师

2012.08-2017.07         北京大学人民医院药剂科,副主任药师

2008.08-2012.07         北京大学人民医院药剂科,主管药师

 

 

社会兼职

中国研究型医院学会药物经济学专委会常委

中国医药教育协会老年药学专委会委员

中国心胸血管麻醉学会心血管药学分会委员

中国医师协会循证医学专委会临床药学学组委员

北京医学会临床药学分会委员

北京药学会临床研究与转化专业委员会委员

北京药理学会合理用药与健康促进分会委员

北京医学会鉴定专家

AJHP、NRRD中文版编委

 

 

代表性论文

1.Ying Zhang#, Yuanyuan Li#, Shiyu He, Xu Hao, Lei Hu, Xinxian Luo, Changqing Yang, Lin Huang#, Yufei Feng#. The correlation

between polymorphisms of pharmacokinetics-related genes and CRP on the metabolism of voriconazole [J].

Drug Metabolism and Disposition, 2022.

2.Shiyu He; Qianhang Shao; Jinxia Zhao; Jialu Bian; Yinyu Zhao; Xu Hao; Yuanyuan Li; Lei Hu; Boyu Liu; Huan He; Lin Huang#;

Qian Jiang#. Factors Influencing Imatinib Exposure in Chinese Patients with Chronic Myeloid Leukemia: from Population

Pharmacokinetics and Pharmacogenetics analyses [J]. Clinical Pharmacokinetics, 2022.

3.Xingxian Luo, Song Jin, Xuecai Xue, Lin Huang# and Gang Cheng#. Voriconazole metabolism is influenced by imatinib,

dasatinib and nilotinib: in vitro and in vivo study [J]. Chemico-Biological Interactions, 2022.

4.Xu Hao, Yuanyuan Li, Jialu Bian, Ying Zhang, Shiyu He, Feng Yu, Yufei Feng#, Lin Huang#. Impact of DNA methylation on ADME

gene expression, drug disposition, and efficacy[J]. Drug Metabolism Reviews, 2022, 54(2):194-206.

5.Ying Zhang, Xu Hao, Kelu Hou, Lei Hu, Jingyuan Shang, ShiYu He, Changqing Yang, Lin Huang# and Yufei Feng#. Impact of

cytochrome P450 2C19 polymorphisms on the clinical efficacy and safety of voriconazole: an update systematic review and

meta-analysis[J]. Pharmacogenetics and Genomics, 2022, 32(7): 257-267.

6.Shiyu He, Jialu Bian, Qianhang Shao, Ying Zhang, Xu Hao, Xingxian Luo, Yufei Feng#, Lin Huang#. Therapeutic Drug Monitoring

and Individualized Medicine of Dasatinib: Focus on Clinical Pharmacokinetics and Pharmacodynamics. [J].

Frontiers in Pharmacology, 2021,12: 797881.

7. Chunyan Zhang, Jing Lei, Yi Liu, Yu Wang, Lin Huang# and Yufei Feng#. Therapeutic Drug Monitoring and Pharmacogenetic

Testing in Northern China. [J]. Frontiers in Pharmacology, 2021,12: 754380.

8.Ying Zhang, Kelu Hou, Fang Liu, Xingxian Luo, ShiYu He, Lei Hu, Changqing Yang, Lin Huang# and Yufei Feng#. The influence

of CYP2C19 polymorphisms on voriconazole trough concentrations: a systematic review and meta-analysis [J].

Mycoses, 2021;64(8):860-873.

9.Huihui Fang, Xiaojuan Wang , Kelu Hou, Zhiying Yu, Lei Hu, Shuai Shao, Guijie Zhang, Yufei Feng# and Lin Huang#.

Association between valproic acid and CYP2C9 gene polymorphism in patients with epilepsy: a meta-analysis [J].

Annals of Translational Medicine, 2021.

10.Xingxian Luo, Taifeng Li, Lei Hu, Silu Liu, Haiyan Zhao, Jiaqi Zhang, Yufei Feng# and Lin Huang#. Differential effects

of C-reactive protein levels on voriconazole metbolism at three age groups in allogeneic hematopoietic cell transplant recipients. [J].

Journal of Chemotherapy, 2021, 33(2): 95-105.

11.Xingxian Luo, Xuecai Xue, Taifeng Li, Yin Zhang, Lin Huang# and Gang Cheng#. Differential impacts of azole antifungal drugs

on the pharmacokinetic profiles of dasatinib in rats by LC-MS-MS [J]. Current Drug Metabolism, 2020, 21(13):1022-1030.

12.Kelu Hou, Zhiying Yu, Yueping Jia, Huihui Fang, Shuai Shao, Lin Huang# and Yufei Feng#. Efficacy and Safety of Ibrutinib in

Diffuse Large B-Cell Lymphoma: A Single-Arm Meta-Analysis [J]. Critical Reviews in Oncology/Hematology, 2020 Aug; 152: 103010. 

13.Shuai Shao, Lei Hu, ZaiGang Han, Kelu Hou, Huihui Fang, Guijie Zhang, Yufei Feng#, Lin Huang#. The effect of ABCB1

polymorphism on sirolimus in renal transplant recipients: a meta-analysis [J].

Translational Andrology and Urology, 2020, 9(2): 673-683.

14.Xingxian Luo,Taifeng Li,Ze Yu,Xuecai Xue, Haiyan Zhao, Na Li, Liping Ma, Jing liu, Changqing Yang, Lin Huang#,

Wangyu Feng#.The impact of azole antifungal drugs on imatinib metabolism in human liver microsomes [J].

Xenobiotic. 2019; 49(7): 753-761.

15.Zhao M, Song JX, Zheng FF, Huang L, Feng YF. Potentially Inappropriate Medication and Associated Factors Among Older

Patients with Chronic Coronary Syndrome at Hospital Discharge in Beijing, China. Clin Interv Aging. 2021 Jun 9; 16:1047-1056.

16.Li TF, Hu L, Ma XL, Huang L, Liu XM, Luo XX, Feng WY, Wu CF. Population pharmacokinetics of cyclosporine in Chinese

children receiving hematopoietic stem cell transplantation. Acta Pharmacol Sin. 2019 Dec; 40(12):1603-1610.

17.Iasella CJ, Kreider MS, Huang L, Coons JC, Stevenson JM. Effect of Selective Serotonin Reuptake Inhibitors on Cardiovascular

Outcomes After Percutaneous Coronary Intervention: A Retrospective Cohort Study. Clin Drug Investig. 2019; 39(6): 543-551.

 

荣誉奖励

2016-2017年度中华医学会临床药学分会优秀临床药师

2013-2014年度北京药学会临床药学之星

2013-2014、2016-2017、2019-2020、2020-2021年度北京大学人民医院优秀共产党员