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Cao Guoying


Name: Cao Guoying

Date of Birth: 20 June 1965

Nationality: Chinese

Address: Department of Pharmacy Beijing Hospital 1 Da Hua Road,

Dong Dan Beijing 100730, P.R.China

Telephone(O): 86 10 85133631

Mobile Phone: 86 13611183512

E-mail address:



1998-2001        MSc  in Medicine Pharmacology, Peking Union Medical College 1982-1987                         

BSc  in Science, School of Pharmacy, Beijing Medical University


Professional Experience

2010.2           Phase I Clinical Trial Training, USA 

2007.4-2008.4Visiting Academic at Department of Pharmacy Practice,

                 Victorian College of Pharmacy, Monash University, Australia

2003.2-2003.6    Research Fellow at the Center for Drug Evaluation, State Food and Drug Administration SFDA, China

1987-present        Department of Pharmacology, Beijing Hospital, P.R.China



Clinical Pharmacotherapy


Research Grants

       2001  Founded by the Ministry of Health, “Optimizing  pharmaceutical  analysis  of nifekalant”

       1996  Founded by the Ministry of Health, “Monitoring the whole blood concentrations of  Cyclosporine A in myasthenia gravis patients”

       1995 Founded by the Ministry of Health, “Comparing four kinds of antibiotics’ concentrations in serum and tissues of rabbits”

       1994  Founded by the Ministry of Health, ” Monitoring the concentrations of phenytoin and carbamazepine in serum, serum ultrafiltration, saliva and studying their relationship”


List of publications

1.      Guoying Cao, Pengyue Ying,Bei Yan Wei Xue,Kexin Li,Aixin Shi,Taohua Sun,Jiling Yan, Xin Hu. Parmkinetics, safety, and tolerability of single and multiple-doses of pinocembrin injection administered intravenously in healthy subjects Journal of Ethnopharmacology.Volume 168(20):31-36.2015.

2.      Guoying Cao, Yang Li, Feng Fei Jin, Xin Hu, et al. Circadian rhythm in serum iron levels. Biol Trace Elem Res. 2012 , 147(1-3):63-66.

3.      Guo-Ying Cao, Ke-Xin Li, Peng-Fei Jin, Xiang-Yang Yue, Chen Yang, Xin Hu. Comparative Bioavailability of Ferrous Succinate Tablet Formulations without Correction for Baseline Circadian Changes in Iron Concentration in Healthy Chinese Male Subjects: A Single-Dose, Randomized, 2-Period Crossover Study. Clin Ther. 2011; 33 (12):2054-2059.

4.      Guoying Cao, FedaEmad Atta Ali, Anima Poudyal, Timo Vaara, Roger L. NationMartti Vaara and Jian Li. Pharmacokinetics of novel antimicrobial cationic peptides NAB 7061and NAB 739 in rats following intravenous administration J Antimicrob Chemother. 2009, Vol.64(5):1067-1070.

5.      Guoying Cao, Feda Emad Atta Ali, Francis Chiu, Alexandre P. Zavascki, Roger L.Nation, Jian Li. Development and validation of a reverse-phase high-performance liquid chromatography assay for polymyxin B in human plasma. J Antimicrob Chemother. 2008, 62:1009-1014.

6.      Alexandre P. Zavascki, Luciano Z. Goldani, Guoying Cao, Silvana V. Superti, Larissa Lutz, Afonso L. Barth, Fabiano Ramos, Márcio M. Boniatti, Roger L. Nation, Jian Li. Pharmacokinetics of intravenous polymyxin B in critically-ill patients. Clin Infect Dis. 2008; 47:1298-1304.

7.      Jianquan Huang, Guoying Cao, Chunhua Sun,et al. Chiral separation of rac-ornidazole and detection of the impurity of (R)-ornidazole in (S)-ornidazole injection and raw material. 2006,Chirality,18:587-591.

8.      KongCai Zhu, GuoYing Cao*, st al. Drug management of hypertension in hemodialysis patients. J. Chin. Pharm. Sci. 2012, 21, 205–210.

9.      KongCai Zhu, Xue Wei, GuoYing Cao* et al. Safety and tolerability of isradipine in Phase I trial in Chinese population. J. Chin. Pharm. Sci. 2014, 23 (3), 194–198.

10.   Di Chen, Guoying Cao, Chunhua Sun. Study of HPLC/ESI-MS-MS analysis of seven hormones in drug materials .Chinese Pharmaceutical Journal.2007; 42:72-74.

11.   Di Chen, Guoying Cao, Dexing Fu Chunhua Sun. "Advances in research of echinocandins drugs as antifungal agents" Chinese Journal of New Drugs.2007;16:1082-1087.

12.   Xiaoyan Yan, Xin Hu, Guoying Cao. Determination of principal agent in oxiracetam sodium chlorideinject ion by HPLC. China Pharmacy.2006; 17:618-620.

13.   Yunfeng Lv, Guoying Cao, Xin Hu, Junren Zhang. Determination of related substance in mildronate injection and assay by high-performance liquid chromatography. Chinese Journal of Pharmaceutical Analysis.2006; 26:358-360.

14.   Guoying Cao, Qiaoling Xu, Dexing Fu. Multitargeted antineoplastic agents -pemetrexed disodium, Adverse Drug Reactions Journal.2006; l8:148-151.

15.   Guoying Cao, Dexing Fu. Anidulafungin: a new echinocandin antifungal agent. Chinese Journal of New Drugs.2005; 14:1358-1361.

16.   Guoying Cao, Runfeng Lu, Xin Hu, Chunhua Sun. Determination of related substances and contents in mildronate and Assay by HPLC-ELSD. Chinese Pharmaceutical Journal.2005; 40:864-866.

17.   Guoying Cao,Dexing Fu. Ertapenem, new carbapenem antibiotics. Chinese Journal of Clinical Pharmacology.2005; 22:74-78.

18.   Guoying Cao, Xiuzhong Wu, Youhua Song. Metabolic characteristics of nateglinide in rat isolated hepatocytes. Chinese Journal of New Drugs.2004; 13:699-703.

19.   Guoying Cao, Xin Hu, Wenxiang Chen. Determination of related substance in nifekalant hydrochloride and it’s injection by high-performance liquid chromatography. Chinese Journal of New Drugs.2004; 13:148-151.

20.   Xiaoyan Yan, Xin Hu, Guoying Cao. Determination of piperacill in and sulbactam sodium in compound injection by RP-HPLC. Chinese Journal of Hospital Pharmacy.2003;23:33-35

21.   Aixin Shi, Kexin LI, Chunhua Sun, Guoying Cao. Study on bioequivalence of domestic bambuterol capsules and imported tablets by high performance capillary zone electrophoresis. Acta Pharmaceutica Sinica.2003; 38:942–945.

22.   Xin Hu, Guoying Cao, Youhua Song. Pharmacokinetics of nateglinide and its racemization during biotransformation in healthy volunteers. Chinese Journal of Clinical Pharmacology.2002; 18:195-199.

23.   YanXiao Yan, Xin Hu, Guoying Cao, Xiaorong He, Qi Yin. Study on the separation of cis-isomer of nateglinide by high pressure liquid chromatographic method. Chinese Pharmaceutical Journal.2002; 37: 444-446.   

24.   Xin Hu, Xiaoyan Yan, Guoying Cao, Xiaorong He. Determination of pazufloxacin mesilate and its related substances by RP-HPLC. Chinese Journal of New Drugs.2002; 11: 862-865.

25.   Guoying Cao, Xin Hu, Youhua Song. Determination of nateglinide enantiomer in human plasma and urine HPLC. Chinese Journal of Pharmaceutical Analysis.2001; 21: 404-407.

26.   Aixin Shi, Kexin Li, Guoying Cao, Chunhua Sun and Youhua Song. Determination of bambuterol and terbutal in human plasma by high performance capillary zone electrophoresis. Chinese Journal of Pharmaceutical Analysis.2001; 4: 290-293.