Nie Xiaoyan

Nie Xiaoyan

 

  

  Peking University Assisstant Professor

 

  Research Areas

  Personalized/Precision Medicine and Pharmacogenetics

  Pharmaceutical Care and Rational Drug Use

  Chronic Disease Management and Health Technology Assessment

  Education and Practice System of Clinical Pharmacy

 

  Education & Positions

  School of Pharmaceutics Sciences, Peking University Health Science Center, B.S., 2006

  Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutics Sciences, Peking University Health Science Center, M.S., 2008

  Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutics Sciences, Peking University Health Science Center, Ph.D., 2017

  Assistant Professor, Department of Pharmacy Administration and Clinical Pharmacy, School of

  Pharmaceutics Sciences, Peking University Health Science Center, 2008-

  Senior Researcher, International Research Centre of Medicinal Administration (IRCMA), Peking University, 2017-

 

  Faculty Accolades

  Prominent Teacher, Peking University Health Science Center, 2018

  Third prize for young teachers' teaching skills competition, Peking University,2017

  Beijing Higher Education Young Elite Teacher Project, Beiing Municipal Education Commission, 2013-2015.

  Excellent Teaching Award, Peking University Health Science Center, 2009&2010

 

  Research Interests

  Our research team spans multiple disciplines, including basic, clinical and social sciences, and bring research finding into clinical pharmacy practice and healthcare services. We focus on the value of new technologies/ pharmacotherapy strategies and how to most effectively and efficiently implement them into health care. The core specialty of our team is personalized (or precision) medicine — an era of healthcare where medical interventions can be tailored to individual patients based on their unique genetic makers. On the developing point of clinical pharmacy in China, our team also conduct researches on pharmacy workforce and pharmacy intervention in different areas.

 

  Grants and funding

  Impacts of PEAR1 gene polymorphisms on protein expression and platelet aggregation in patients with ticagrelor, Funded by National Natural Science Foundation of China。No.81803497. Principal Investigator

  Effects of PEAR1 gene polymorphisms and haplotypes on the personalized use of antiplatelet drugs. Funded by Supported by Beijing Municipal Natural Science Foundation, No.7184223, Principal Investigator

  Study on the strategy of adjusting the dosage of antibiotics in patients receivingContinuous renal replacement therapy(CRRT) treatment. Funded by Beiing Municipal Education Commission, No.YETP0064, Principal Investigator

  Evaluation of prognosis efficacy of platelet function test in patients with coronary heart disease after antiplatelet therapy, Funded by key lab of health technology assessment, Ministry of Health, No.FHTA2017-01, Principal Investigator

  Exploration of clinical pharmacy service mode in community pharmacy in China, Funded by Peking University Health Science Center, No. BMU20090525-123, Principal Investigator

 

  Publications

  Xiaoyan Nie,Junlei Li, Sibei Qin, Yu Fu, Guangkai Liang, Luwen Shi*, Hong Shao, Jian Liu#, Yun Lu. Genetic variations in PEAR1 associated with cardiovascular outcomes in chinese patients with acute coronary syndrome. Thrombosis research . 2018;163:77-82.

  Junlei LI, Yu Fu, Sibei Qin, Guangkai Liang, Jian Liu ,Xiaoyan Nie*, Jing Chen, Luwen Shi, Hong SHAO, Yun Lu.  Association  between  P2RY12   gene  polymorphisms  and  adverse  clinical  events  in  coronary  artery  disease patients treated with clopidogrel: a systematic review and meta-analysis. Gene . 2018;657:69-80.

  Xiaoyan Nie, Junlei Li, Yong Zhang. Yang Xu, Xueli Yang, Yu Fu, Guangkai Liang, Yun Lu, Jian Liu#, Luwen Shi#. Haplotype of platelet receptor P2RY12 gene is associated with residual clopidogrel on-treatment platelet reactivity. Journal of Zhejiang University SCIENCE B(Biomedicine & Biotechnology). 2017;18(1):37-47.

  Xiaoyan Nie, Yang Xu,Yu Fu, Junlei Li, Guangkai Liang, Yong Zhang, Yun Lu, Jian Liu#, Luwen Shi#. The correlation and consistency of light transmission aggregometry and thrombelastography in identifying high clopidogrel on-treatment platelet reactivity in patients with acute coronary syndrome. Journal of Chinese Pharmaceutical Sciences. 2016;25 (11):833–840.

  Jian Liu*, Xiaoyan Nie*, Yong Zhang, Yun Lu, LuWen Shi#, WeiMin Wang#. CYP2C19*2 and other allelic variants affecting platelet response to clopidogrel tested by thrombelastography in patients with acute coronary syndrome. Chinese Medical Journal. 2015; 128(16):2183-2188. (*Co-first authors).